منابع مشابه
Endothelial Cell Self-fusion during Vascular Pruning
During embryonic development, vascular networks remodel to meet the increasing demand of growing tissues for oxygen and nutrients. This is achieved by the pruning of redundant blood vessel segments, which then allows more efficient blood flow patterns. Because of the lack of an in vivo system suitable for high-resolution live imaging, the dynamics of the pruning process have not been described ...
متن کاملDecrease in VEGF expression induces intussusceptive vascular pruning.
OBJECTIVE The concept of vascular pruning, the "cuting-off" of vessels, is gaining importance due to expansion of angio-modulating therapies. The proangiogenic effects of vascular endothelial growth factor (VEGF) are broadly described, but the mechanisms of structural alterations by its downregulation are not known. METHODS AND RESULTS VEGF(165)-releasing hydrogels were applied onto the chick...
متن کاملWhen It Is Better to Regress: Dynamics of Vascular Pruning
Blood vascular networks in vertebrates are essential to tissue survival. Establishment of a fully functional vasculature is complex and requires a number of steps including vasculogenesis and angiogenesis that are followed by differentiation into specialized vascular tissues (i.e., arteries, veins, and lymphatics) and organ-specific differentiation. However, an equally essential step in this pr...
متن کاملNeural Network Pruning and Pruning Parameters
The default multilayer neural network topology is a fully interlayer connected one. This simplistic choice facilitates the design but it limits the performance of the resulting neural networks. The best-known methods for obtaining partially connected neural networks are the so called pruning methods which are used for optimizing both the size and the generalization capabilities of neural networ...
متن کاملPruning Moves
T concept of dominance among nodes of a branch-and-bound tree, although known for a long time, is typically not exploited by general-purpose mixed-integer linear programming (MILP) codes. The starting point of our work was the general-purpose dominance procedure proposed in the 1980s by Fischetti and Toth, where the dominance test at a given node of the branch-and-bound tree consists of the (po...
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ژورنال
عنوان ژورنال: Chest
سال: 2021
ISSN: 0012-3692
DOI: 10.1016/j.chest.2020.10.006